In recent studies, it was acceptable to use the modified duke criteria for endocarditis that is attributed to pm and defibrillator leads 1,6,10,11 tables 1 and and2. Because sensitivity of the modified duke criteria for infective endocarditis and echocardiography is lower in cied endocarditis since it is harder to detect infection on the device electrode tip or endocardial areas in contact with the electrode tip, fdgpetct or radiolabeled leukocyte scintigraphy imaging is the preferred means for. Endocarditis diagnostic criteria duke criteria calculator. Echocardiogram supportive of infective endocarditis. Modified dukes criteria for diagnosis of infective endocarditis pdf. Established in 1994 by the duke endocarditis service and revised in 2000, the duke criteria are a collection of major and minor criteria used to establis h a di agnosis of ie 23. Fulfilling the criteria, and a subsequently definitive diagnosis includes either having two major criteria, one major and three minor criteria, or five minor criteria. Histologic, vegetation or intracardiac abscess present, confirmed by histology showing active endocarditis, short of definite, but not rejected, no pathologic. The endocarditis diagnostic duke criteria calculator evaluates both major and minor diagnostic criteria.
Modified dukes criteria to diagnose acute infective. Early and accurate diagnosis of infective endocarditis is crucial because delayed treatment negatively affects outcome. Duke criteria for infective endocarditis diagnostic criteria for endocarditis. Between 1985 and 2001, 41 episodes of ie were documented in 40 children median. Duke criteria for infectious endocarditis diagnosis. Under the modified duke criteria, the clinical criteria for definite infectious endocarditis includes. The epidemiology of ie has shifted recently with an increase in health careassociated ie. Acute infective endocarditis aie is a difficult disease to suspect and diagnose. Endocarditis team and, when needed, with external visit to the reference centre. Individual value of each of the duke criteria for the diagnosis of infective endocarditis. Click on the image or right click to open the source website in a new browser window. Established in 1994 by the duke endocarditis service and revised in 2000, the duke criteria are a collection of major and minor criteria used to establish a diagnosis of infective endocarditis.
Guidelines for the management of infective endocarditis. Pathologic criteria are histological or culture confirmation ofpathologic criteria are histological or culture confirmation of vegetation or emboli. Microbiologic typical microorganisms isolated from. The duke criteria should be used as overview of management of infective endocarditis in adults. The modified duke criteria for diagnosing infective endocarditis include one or more of these pathologic criteria. One of the reasons is that the cardiac changes do not. Predicting risk of endocarditis using a clinical tool. Prevention the endocarditis team diagnosis definition of the terms used in the esc 2015 modified criteria for diagnosis of ie, with modifications in main principles of prevention of infective endocarditis boldface 1.
Minor criterion includes predisposing heart condition or iv drug use, fever, vascular phenomena, immunologic. Contribution of pet imaging to the diagnosis of septic embolism in patients with pacing lead endocarditis. The duke criteria for diagnosing infective endocarditis are specific. Culturenegative infective endocarditis cne is a diagnostic problem in spite of improved echocardiographic and blood culturing techniques. Infective endocarditis ie is a rare, lifethreatening disease that has longlasting effects even among patients who survive and are cured.
Evaluation of new clinical criteria for the diagnosis of infective. The modified duke criteria are a set of clinical criteria set forward to establish the diagnosis of infective endocarditis. Excludes single positive cultures for coagulasenegative staphylococci and organisms that do not cause endocarditis. The duke criteria are a set of clinical criteria set forward for the diagnosis of infective endocarditis. Modification of the diagnostic criteria proposed by the duke endocarditis service to permit improved diagnosis of q fever endocarditis. Echocardiographic evidence of ie was defined as presence of an oscillating intracardiac mass, myocardial abscess, new valvular regurgitation, or new dehiscence of a prosthetic valve. Modified duke infective endocarditis criteria university of. Infective endocarditis requiring intensive care unit stay is increasing, and. These images are a random sampling from a bing search on the term duke criteria for infectious endocarditis diagnosis. Diagnostic value of imaging in infective endocarditis. This is a pdf document titled modified dukes criteria for diagnosis of infective endocarditis. The duke criteria for infective endocarditis provides standardized diagnostic criteria for endocarditis. Individual value of each of the duke criteria for the. Only patients who met the modified duke criteria for definite endocarditis were included.
A definitive clinical diagnosis is made based on the presence of 2 major criteria, 1 major criteria and 3 minor criteria, or by 5 minor. Clinical criteria for definite endocarditis requires two major criteria, or one major and three minor criteria, or five minor criteria. The accepted criteria for diagnosis of ie are the modified. Modified dukes criteria for diagnosis of infective. The term predisposing heart condition is used as an indication of antimicrobial prophylaxis to prevent infective endocarditis ie and as a criterion for diagnosing ie according to modified duke criteria. Retrospective case study in a tertiary pediatric hospital. Infective endocarditis european society of cardiology.
If all are positive, diagnosis is definite see evidence for exceptions. To assess the value of each duke criteria for the diagnosis of infective endocarditis ie. If 2 primary criteria, or 1 primary criterion and 3 secondary criteria, or 5 secondary criteria, are present, infectious endocarditis is probable. It is the dedication of healthcare workers that will lead us through this crisis. This conversion might result in character translation or format errors in the html version. The purpose of this survey was to elaborate clinicians knowledge and opinion on relevant heart conditions as a duke minor criterion for the diagnosis of ie. We conducted the present study to estimate the proportion of cne in patients with infective endocarditis, to investigate data regarding risk factors, and to evaluate the duke and the modified beth israel criteria in patients with cne. Infective endocarditis ie is a noncontagious infection of the endocardium and heart valves. Supplementary appendix this appendix has been provided by the authors to give readers additional information about their work. Antibiotic treatment of infec tious endocarditis depends on whether the involved valve is native or.
University of pennsylvania health system antimicrobial use. You can change the settings or obtain more information by clicking here. The duke criteria for endocarditis are summarized below. New criteria for diagnosis of infective endocarditis. Objectives the purpose of this study was to assess the value and limitations of duke criteria for the diagnosis of infective endocarditis ie. Value and limitations of the duke criteria for the. Major criterion includes positive blood culture for typical infective endocarditis organisms, and echocardiogram with oscillating intracardiac mass. According to the duke criteria, diagnosis of infective endocarditis can be definite, possible, or rejected. Diagnosis diagnosis of ie is frequently difficult, particularly in some subgroups prosthetic valve ie pve, intracardiac device and bloodculture negative ie bcnie. Tee recommended as first test in the following patients. Worsening or changing of preexisting murmur not sufficient. Duke criteria for infective endocarditis inflammatory.
Clinical criteria for possible endocarditis requires at least one major criterion and one minor criterion, or three minor criteria. Signs and symptoms of bacterial endocarditis are diverse. Suspect ie and consider the duke criteria in patients with. The modified duke criteria stratify patients into the following categories. Duke criteria for infective endocarditis durack dt, lukes as, bright dk. At least 2 positive blood cultures with typical pathogens before the start of antibiotic therapy. In the absence of classical features fever, cardiac murmur, and peripheral vascular stigmata the diagnosis of infective endocarditis ie may be.
Although the sensitivity and specificity of the duke criteria for the diagnosis of infective endocarditis ie have been validated. Endocarditis diagnostic criteria modified duke criteria. Management considerations in infective endocarditis. Diagnostic criteria and problems in infective endocarditis. Duke criteria for infective endocarditis radiology.
Ie disproportionately affects those with underlying structural heart disease and is increasingly associated with health care contact, particularly in patients who have intravascular prosthetic material. For adequate diagnostic sensitivity, transesophageal echocardiography is the preferred modality used in patients designated highrisk or those in. The diagnosis of ie was rejected in all cases in accordance with the duke criteria i. Infective endocarditis is a microbial infection of the endothelial surface of the heart 11. Should be applied to patients in whom there is a high clinical suspicion of ie. Clinical criteria are 2 major, 1 major plus 3 minor or 5 minor criteria e. Value and limitations of the duke criteria for the diagnosis of. Proposed modifications to the duke criteria for the diagnosis of infective endocarditis. A total of consecutive cases of suspected infective endocarditis in patients evaluated in a tertiary care hospital from to were analyzed using new diagnostic criteria for endocarditis. Assesment of the duke criteria for the diagnosis of infective. Bacterial endocarditis is a microbial infection of the endothelial surface of the heart. Duke criteria for the diagnosis of endocarditis definite. These were originally proposed in 1994 to help establish the diagnosis of endocarditis.